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          Pranovo Biotech 10808-C02E 說明書

          更新時間:2017-08-09      點擊次數:2478

          世界*實驗材料供應商 Pranovo Biotech正式授權上海起發為其中國代理, Pranovo Biotech在一直是行業的*,一直為廣大科研客戶提供zui為的產品和服務,上海起發一直秉承為中國科研客戶帶來的產品,的服務,簽約 Pranovo Biotech就是為了給廣大科研客戶帶來更加完善的產品和服務,您的滿意將是我們zui大的收獲

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          Pranovo Biotech是一家不斷發展的生物技術公司,我們主要生產高度純化的重組蛋白/抗體,包括細胞因子,生長因子,趨化因子,激素,酶,病毒抗原和許多其他重組蛋白,用于癌細胞因子相關產品的研究團體,凋亡,內分泌學,免疫學,神經科學,蛋白酶和干細胞研究。

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          • 抗體
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          • 色譜介質
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          ??Cynomolgus BCA-1/ BLC/ CXCL13 Protein (His Tag)

          • Catalog: 10808-C02E

          Please Choose:Application

          Antibody Production; ELISA; Protein Array; Western Blot;

           

          Size   1mg 

               50μg

           

          Cynomolgus BCA-1/ BLC/ CXCL13 Protein (His Tag)

          For Research Use Only

          Synonym : 

          BCA-1, BLC, CXCL13, C-X-C Motif Chemokine 13

           

          Source:

          Recombinant Cynomolgus BCA-1/ BLC/ CXCL13 Protein, Val 23 - Pro 109(NP_001028052.1) was expressed in E.coli cells.

           

          Molecular Characterization:

          Recombinant Cynomolgus BCA-1/ BLC/ CXCL13 Protein, with a 6*His tag at the N-terminus, consists of 103 amino acids and has a calculated molecular mass of 12.4 kDa. The apparent molecular mass of Recombinant Cynomolgus BCA-1/ BLC/ CXCL13 Protein is approximay 14 kDa in SDS-PAGE under reducing conditions due to glycosylation.

           

          Sequence:

          Cynomolgus BCA-1/ BLC/ CXCL13 Protein (His Tag)

           

          Endotoxin:

          <1.0 EU per μg of the Recombinant Cynomolgus BCA-1/ BLC/ CXCL13 Protein by the LAL method.

           

          Purity:

          >90% as determined by SDS-PAGE.

           

          SDS-PAGE:

          Cynomolgus-BCA-1-BLC-CXCL13-Protein-His-Tag

           

          Formulation:

          Lyophilized from sterile 10 mM Tris, 250mM  NaCl, pH 8.0

          Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA.

          Contact us for customized product format or formulation.

           

          Storage:

          Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at:

          • 4-8℃ for 1 year in lyophilized state

          • 4-8℃ for 1 month under sterile conditions after reconstitution

          • -20℃ to -70℃ for 3 months under sterile conditions after reconstitution

           

          Reconstitution:

          Reconstitution instruction will be sent along with the products. Please refer to it for detailed information.

           

          Background:

          Cynomolgus CXCL13, also known as BCA-1 ( B-cell-attracting chemokine-1 ) or BLC ( B-lymphocyte chemoattractant ), is a major regulator of B-cell trafficking. BCA-1/ BLC/ CXCL13 Protein is a small cytokine belonging to the CXC chemokine family. BCA-1/ BLC/ CXCL13 and its receptor CXCR5 control the organization of B cells within follicles of lymphoid tissues. BCA-1/ BLC/ CXCL13 Protein is known to dictate homing and motility of B cells in lymphoid tissue and has been implicated in the formation of ectopic lymphoid tissue in chronic inflammation. The increased level of BCA-1/ BLC/ CXCL13 Protein is a feature of systemic lupus erythematosus (SLE) that correlates with disease activity. Furthermore, BCA-1/ BLC/ CXCL13 Protein might be a readily available surrogate marker to monitor the extent of aberrant B-cell (dys-)function. The vascular endothelial BCA-1/ BLC/ CXCL13 Protein expression may be consequent to transcytosis. In Primary central nervous system lymphoma (PCNSL), expression of BCA-1/ BLC/ CXCL13 Protein by malignant lymphocytes and vascular endothelium may influence tumor development and localization to central nervous system (CNS). BCA-1/ BLC/ CXCL13 Protein expression is a distinctive feature of angioimmunoblastic T-cell lymphoma, providing further support for the germinal center T-helper cell as the cell of origin for this neoplasm. Furthermore, BCA-1/ BLC/ CXCL13 Protein, a chemokine that may participate in tumor pathogenesis and is a potential target for novel therapies.

           

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