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APC Human Activated Protein C
Activated Protein C （APC） is a serine protease derived from the two chain vitamin K dependent zymogen, Protein C. APC inhibits blood coagulation through the selective inactivation of the cofactors Va and VIIIa. APC is prepared from protein C by activation with purified thrombin. This thrombin is removed after activation by ion exchange chromatography. Activated Protein C purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.
Buffer composition = 20 mM Tris-HCl/0.1 M NaCl/ pH 7.4
*Extinction Coefficient （1%） = 14.5
Molecular Weight = 56,000 daltonsAlso available: des-Gla-Human Activated Protein C
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